Benzalkonium chloride is a quaternary ammonium compound and it is the most commonly used antimicrobial preservative. It was initially used in hard contact lens solutions but is now ubiquitous. Currently, it can be found in most topical multi-use ophthalmic preparations.
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It is used as a solubilizer and emulsifying agent in foods, cosmetics, and pharmaceuticals, often as an ointment base. It is used as an oil in water (O/W) emulsifier for creams/lotions, and a wetting agent.